Senate bill · S. 545 (119th Congress)
Combating Illicit Xylazine Act
U.S. Senate
Sponsor: Catherine Cortez Masto (U.S. Senator for Nevada, Democratic)
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From Congress.gov and official rosters. This record was last updated Aug 3, 2026. About our data
Summary
Combating Illicit Xylazine Act This bill regulates xylazine under the Controlled Substances Act (CSA). Xylazine, also known as tranq , is a nonopioid sedative and pain reliever that is approved for use in animals. Recently, the Drug Enforcement Administration (DEA) has reported an increase in trafficking of fentanyl mixed with xylazine. This bill adds xylazine, including its salts, isomers, and salts of isomers, to schedule III of the CSA. Schedule III controlled substances, including anabolic steroids, buprenorphine, and ketamine, have less potential for abuse than a schedule I or II substance, have a currently accepted medical use, and have low or moderate risk of dependence if abused. Under the bill, manufacturing, distributing, or dispensing xylazine, or possessing with intent to manufacture, distribute, or dispense xylazine for illicit use is subject to criminal penalties under the CSA. The bill also requires xylazine transactions to be tracked in the drug reporting system maintained by the DEA. The bill exempts from registration under the CSA persons and entities that possess xylazine (1) lawfully dispensed by a veterinarian or pharmacy and (2) for an animal or for use in certain animal-control or wildlife programs. The bill also exempts xylazine manufacturers from the CSA's physical security requirements. Finally, the bill requires the DEA, in coordination with the Department of Health and Human Services (HHS), to provide Congress with a report on how the agencies previously determined whether xylazine should be a controlled substance, including the full text of HHS's recommendations to the DEA for scheduling xylazine.
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Where it stands
Out of committee and scheduled for a vote by the full chamber.
- Introduced
- In committee
- Up for a vote
- Passed one chamber
- Passed
- Enacted
Committee
House Committee on the Judiciary · U.S. House of Representatives
Also referred to Senate Committee on the Judiciary · U.S. Senate.
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Cosponsors
35
Cosponsors listed on Congress.gov, shown A to Z.
- Republican19
- Democratic15
- Other1
This bill has cosponsors from more than one party.
Shown in neutral colors by design; Agora is non-partisan.
- Amy Klobuchar
- Angus S. King, Jr.
- Ashley Moody
- Ben Ray Luján
- Chuck Grassley
- Cindy Hyde-Smith
- Cynthia M. Lummis
- David McCormick
- Jacky Rosen
- James C. Justice
- James E. Risch
- James Lankford
Show the full list (35 names)Show fewer cosponsors
- Jeanne Shaheen
- Jeff Merkley
- John Cornyn
- John Fetterman
- Katie Boyd Britt
- Kirsten E. Gillibrand
- Margaret Wood Hassan
- Maria Cantwell
- Mark Kelly
- Marsha Blackburn
- Michael F. Bennet
- Mike Crapo
- Richard Blumenthal
- Richard J. Durbin
- Rick Scott
- Roger F. Wicker
- Ruben Gallego
- Shelley Moore Capito
- Ted Budd
- Ted Cruz
- Thom Tillis
- Tim Kaine
- Todd Young
Related bills
As identified by Congress.gov.
Full history
- Apr 15, 2026
Reported out of committee
Committee on the Judiciary. Reported by Senator Grassley with an amendment in the nature of a substitute. Without written report.
- Apr 15, 2026
Reported out of committee
Committee on the Judiciary. Reported by Senator Grassley with an amendment in the nature of a substitute. Without written report.
- Apr 15, 2026
Reported out of committee
Committee on the Judiciary. Reported by Senator Grassley with an amendment in the nature of a substitute. Without written report.
- Apr 15, 2026
Introduced
Placed on Senate Legislative Calendar under General Orders. Calendar No. 372.
U.S. Senate
- Apr 15, 2026
Placed on Senate Legislative Calendar Under General Orders. Calendar No. 372.
Placed on Senate Legislative Calendar under General Orders. Calendar No. 372.
U.S. Senate
Show full history (7 earlier events)Show less history
- Mar 26, 2026
Reported out of committee
Committee on the Judiciary. Ordered to be reported with an amendment in the nature of a substitute favorably.
- Mar 26, 2026
Reported out of committee
Committee on the Judiciary. Ordered to be reported with an amendment in the nature of a substitute favorably.
- Mar 26, 2026
Reported out of committee
Committee on the Judiciary. Ordered to be reported with an amendment in the nature of a substitute favorably.
- Feb 12, 2025
Introduced
Introduced in U.S. Senate
U.S. Senate
- Feb 12, 2025
Referred to committee
Read twice and referred to the Committee on the Judiciary.
- Feb 12, 2025
Referred to committee
Read twice and referred to the Committee on the Judiciary.
- Feb 12, 2025
Referred to committee
Read twice and referred to the Committee on the Judiciary.
Read the record
- Read on Congress.gov (opens in a new tab) The official record on Congress.gov.